AYE Exocure Advanced Technology
Our R&D Efforts
NanoExtract Technology, which forms the foundation of AYE Exocure’s R&D vision, is based on transforming plant-derived extracts into particles below 200 nanometers through advanced purification and size-reduction processes. These particles retain their natural structures, are biologically compatible, and possess a double-layer lipid membrane structure.
Through this technology, the neuroactive components within botanical extracts are not only reduced in size but also:
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Stabilized in a way that may help them cross the blood-brain barrier,
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Enabled to reach target areas without the need for carrier systems,
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Supported in their biological interactions at the cellular level,
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Enhanced in their biocompatibility due to their natural and additive-free composition.
These nano-structures may help support intercellular communication in a manner similar to the body’s natural carrier systems. Findings in the scientific literature suggest that such structures may contribute to maintaining balance in biological processes such as oxidative stress and supporting renewal mechanisms.
Traditional botanical extracts can be degraded in the digestive system, face limitations in absorption, and remain restricted in biological interaction. NanoExtract Technology may help overcome these limitations by:
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Supporting the effectiveness of components even at lower doses,
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Helping interactions begin at earlier stages,
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Contributing to enhanced biological availability.
In all AYE Exocure formulations, this technology represents not only a production model but also an outcome of scientific responsibility and nature-respecting innovation.
Scientific Studies and International Recognition
In 2024, our scientific study examining the physicochemical structure of our product was accepted to the PubScholars International Neurology Conference, one of the most reputable global events where the latest scientific developments in the nervous system are shared.
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The study evaluated the stability profile, zeta potential, and UV/Vis spectrum analyses of the plant-derived nanoparticles in our formulation. The findings provided insight into the stability of these structures under environmental conditions and their properties that may help support interactions with biological systems. Conducted at the laboratories of Hacettepe University, these analyses offered a preliminary scientific evaluation of the technical components of our formulation.
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After a thorough review by the scientific committee, this study was approved for publication as a full text in the conference proceedings. This achievement demonstrates that our formulation is considered valuable for scientific evaluation not only at the ingredient level but also in its structural and technological aspects on international platforms.
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In 2025, our multi-center preclinical research was accepted to AD/PD 2025 – International Conference on Alzheimer’s and Parkinson’s Diseases, held in Vienna and recognized as one of the most prestigious global scientific events on neurological changes related to the nervous system.
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This study involved a comprehensive experimental design using cell culture models, animal studies, and observational human data, monitoring biological markers such as cell viability, specific biomarker levels, oxidative stress parameters, and Amyloid Beta accumulation. The results indicated that the developed formulation may help support the balance of certain biological processes.
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The study was evaluated by the AD/PD 2025 Scientific Committee and included in the congress program as a poster presentation. This recognition highlights that our formulation is not only composed of innovative components but is also built on a foundation of scientific research.
